Lub-DUB! The second heart sound corresponds to both pulmonary and aortic valve closing during ventricular diastole. Yet, when either tricuspid or mitral valve can’t open properly, turbulence appears and also does the murmur, specially at late diastole, when the atria contract for that final kick into the end diastolic volume. From there a series of pathological changes occur. Check them out:
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-The Plague Doctor